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Levels of Evidence
Levels of Evidence: Studies of Therapeutic Effectiveness
| Level | Criteria |
|---|---|
| 1a | Systematic review of randomized controlled trials |
| 1b | Individual randomized controlled trial |
| 2a | Systematic review of cohort studies |
| 2b | Individual cohort study |
| 3a | Systematic review of case-control studies |
| 3b | Individual case-control study |
| 4 | Case series |
| 5 | Expert opinion without explicit critical appraisal or based upon physiology or bench research |
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